Sunday, June 28, 2009
Dear Mary
Tuesday, June 23, 2009
Results of vet visit - no vincristine today
wbc too low at 2.12 from 3.26 last week
Dr P was quite confident that we could do the chemo today - vincristine but his haematology test indicated other wise. She was pleased with his condition for last week and told me that the Endoxan was a little milder than the vincrsitine and so he should be more energetic. She was also pleased with his prep results. He has put on a little weight and is now 3.54 from 3.5 kg.
I am very pleased that his liver seemed better with his ALT at 90 (normal 20-100). His last test had his ALT at 105. The milk thistle may have done a lot of good here. His BUN is 22 from 27 (normal 10-30) and his CRE is 1.2 from 1.5 (normal 0.3-2.1). Even his TP has gone down to 8.7 from 9.0 (normal 5.4- 8.2). I think this would be the result of syringing him with about 60 ml of water daily. These last 2 days I had only syringed him with about 10 ml of water since he suddenly decided to drink by himself on Saturday. But I am very kiasu and syringed him anyway as I don't think he drinks enough water. His GLU h/w has gone up to 165 from128 (normal 70-150). She didn't think this was a concern though. I read that this could be due to stress. He really does not need diabetes in his life now!
He is down to 1/4 tab of his steroid prednisolone too. I can only hope that next week his wbc is good enough for his chemo.
Sunday, June 21, 2009
Sunday Finds Me...
Saturday, June 20, 2009
I am not talking to you ...
Megat is getting royally fed up with the mushroom cocktail...
Megat fussed quite a lot with his cocktail and water to night. At least he had his pill down flat. For that I am grateful. Its time to give him papayas intaed of pumpkin as he doesn't like the taste anymore. He ate all of it though :) I tried tuna water today but that didn't go swimmingly. But I will persevere. He had 10 ml of syringed water as he did't like his tuna water this afternoon :)
Saturday notes
Are you looking at me san?
Megat is surprisingly well for a cat with drugs in his system. He has not lost much energy. Rather he has been walking about rather spritely. His toilet habits are regular and I am glad to see that even this morning he had left me poo in his litter and 2 big pee clumps. He still runs off when he sees me and no longer hangs about on the cat blankets on the bed as he knows it make shim easy to pick up :) So he has taken to hiding under the table, right in the innermost corner so he almost disappears from view. I have yet to give him the Solid Gold tuna water formula as yesterday he had his usual sub q and supplements which gives him a lot of water. This morning, he had some Tiki with a lot of jelly for his morning water consumption. Grandma tells me tha he does drink form his Dora cup but I have yet to see it for myself. This is what he looks like this morning - bright alert eyes and a suspicious glance :)
Thursday, June 18, 2009
Update after Cyclophosphomide
Megat has been very regular the last two nights with his poo. I am glad that he has done it in his own litter every night from Tuesday 160609. It is easier for me to keep track. I have included 20 ml of duphalac in his supplements with either papaya or pumpkin, the usual mushroom combination, ling zhi and milk thistle. Then I had given him about 20 ml of water. This has been the usual regimen with him for the last 2 days and for 2 days in a row, he has managed to poo. The poo is rather firm. So maybe this is the best formula for him at this time. He does not go during the day though except to pee.
He takes his formula with good grace with only minor fussing and grandma and Cousin R have been very good at helping me. Of cos Megat's antics made them laugh too so the whole process was not too arduous for everyone, Megat included. He ate is pumpkin with much better grace though. Maybe its because he is used to the taste of pumpkin.
I would not be able to see if there is blood in his urine as he does it in his litter but I am sure that with all that water in his system, this would not happen. I was glad to see that he went to pee quite soon afetr we got back from the hospital as that means some of the the drug would have gone through his system and out. He urinates regularly which is a good thing as 37% - 82% (20% intact) would be excreted through urine.
He is doing much better with the Cyclophosphomide and is alert and active. Maybe it is the supplements that have made such a difference. He still sleeps but not any more than he used to do before the chemo. He is getting into the swing of asking for scritches and brushing regularly and more important, he still grooms himself as carefully as before. :)
Tuesday, June 16, 2009
2nd chemo session cyclophosphamide
"I know what you are up to san. Don't think I don't!"
Megat at his hanging basket right after dinner.
Megat sitting with me after his supplements. Furgive and furrget...
Saturday, June 13, 2009
Saturday update for 2nd week
Thursday, June 11, 2009
Letter to san
Finally!
I surprised Megat when he was trying to go...in the middle of the living room!!! Aiyoh! Cat! But I noticed that eventhough he strained himself, there was no way he was going to be able to poo at all. He saw me and hid under the couch as he asociates me with many unpleasant experiences. I decided to follow my instincts, caught him from under the table and brouhgt him to the bathroom where the boxes were. He preferred to do it on the mat and I let him be. After a few minutes, I noticed that he had a difficult time and so removed the hard poo for him. Of course I could not help him completely and the poor kitty and to strain again and again. I spoke to him softly and he tried again. By this time, all the boys were waiting outside the bathroom door quietly. Finally with one final strain, the hard poo came out followed by the softer ones. SUCCESS! He sat quietly and I gave him a treat which he ate slowly and happily.
Wednesday, June 10, 2009
Our Mushroom Defense
Dietary Supplement
Source Naturals Mushroom Immune Defense is a blend of mushroom mycelia and extracts from 16 of the most well-studied species of health-supportive mushrooms. Although the exact mechanisms of action in the body are not yet fully understood, researchers propose that constituents of these mushrooms may support natural killer (NK) cell, T-cell, and macrophage activity, and cytokine production. By carefully combining these mushrooms and fortifying them with extracts, Source Naturals Mushroom Immune Defense offers a broad-spectrum, high potency, complete mushroom product.
Calories 10
Total Carbohydrates 2 g DV <2%
Vitamin C (as ascorbic acid) 100 mg DV 170%
Shiitake Mycelia Biomass 200 mg †
Reishi Mycelia Biomass 200 mg †
Maitake Mycelia Biomass 200 mg †
Turkey Tail Mycelia Biomass 150 mg †
Proprietary Blend: 1.3 g †
Agaricus blazei Mycelia Biomass, Hericium erinaceus Mycelia Biomass, Flammulina velutipes Mycelia Biomass, Tremella Mycelia Biomass, Schizophyllum commune Mycelia Biomass, Artist's Conk Mycelia Biomass, Poria Mycelia Biomass, Zhu Ling Mycelia Biomass, Pleurotus ostreatus Mycelia Biomass, Cordyceps sinensis Mycelia Biomass, Cordyceps militaris Mycelia Biomass, Armilleria mellea Mycelia Biomass, Shiitake Mushroom Extract, Reishi Mushroom Extract (6:1), Maitake Mushroom Extract (10:1), Turkey Tail Mushroom Extract (8:1), Cordyceps sinensis CS-4 Standardized Extract (0.1% adenosine), Agaricus blazei Mushroom Extract (4:1), and Dr. Nanba's Maitake Beta-Factor™ (beta-glucan) Fraction††.
Chemo Review 1
Megat's hematology test did not allow his second chemo session as his wbc was 1.88 from 3.97. As this was below the required level of 2.5, Dr P said his cyclophosphamide IV would be postponed till next week when she hoped it would be higher. So he has to only take one tab of prednisolone at 5mg per day. Of course with this , his LYM has decreased to 1.23 from 2.18 (normal 1.5 to 7). The doc recommended that I give him some lin zhi mushrooms to increase his immune system. I had actually got him tablets of 16 mushrooms from 1herb.com that seemed to help other people and their pets to deal with their immune system and cancer and so will give him that instead as well as the milk thistle for his liver.
So essentially his supplement, as of today, consists of 1.5 ml of duphalac and 1 dessertspoon of mashed papaya (he still has constipation) + 2 tablets of mushroom formula and 6 drops of milk thistle. I read that it would be better to give him an aggressive dose of mushroom in the first few weeks of his cancer but as he still has to get used to it, I am only giving him 2. If 2 is the rec dose for an adult, it should be okay for a cat with lymphoma. I will put the pic up once my cpu is ok.
He was also a little dehydrated as he was not drinking much last week and so, if he still refuses to drink this week, I was to syringe him with 10ml of water every hour. Dr P thought that 1x sub q would be enough if I can give him the water in syringes. Of course, as though he understood the doc, Megat immediately drank water from his Dora cup when he came back from his consultation and even today, he continued to drink throughout the day although I would have liked it if he had drunk more. He had drunk more before the chemo.
On the brighter side, his platelets has increased to 90 from 33 although his PCV has stayed at a constant rate of 26 %. His ALT, on the other had, had decreased to 105 from 122.
Dr P also reported that his physical state is good although he is thin. But she recommended that he stays on his renal diet and I was not to subsititute it with another one, even if the diet has no grain in it. I would put water in his dry food but I know he would eat none of it wet. I had tried this the first time he had to go on the diet. :(
Anyway, he is looking brighter and has much more energy but maybe this could be due to the fact that he did not have his chemo this week.
Tuesday, June 9, 2009
Poo tales best left unread for the squeamish
The Pill-the-cat saga
Sunday, June 7, 2009
Constipation
PS: Eversince I gave him pumpkin, he has been very regular and it was today that I noticed he was not going regularly! I immediately thought of that this might be one of the side effects of the treatment. :(
I thought I should post the answer since I had bought it.
My question
My cat has not been able to poo the whole of today. he tried twice but was unsucessful. he is 13 years old and has just had Vincristine IV on tuesday 020609 and 1.5 tablets of pendnisone 5mg. Can I give him anything to help him with this constipation? I gave him some pumpkin but it didnt help him.
The answer
Hi,
Oftentimes milk will be a natural laxative in cats. I would try giving him several tablespoons of milk to see if that will help soften his stool. I don't generally find that increasing the fiber in a cat's diet helps with constipation, so I wouldn't give any more of the pumpkin. Sometimes giving a hairball medication, like laxatone or petromalt, can help stool "slide" easier.
The more liquid you can get in your cat, the better. If he likes canned food, I would feed him that and actually mix a little more water in it to make it soupier. If he likes tuna, I recommend making "tuna cubes"--1 can tuna in a blender full of water. Mix well, then freeze as ice cubes. Give several cubes each day. Diluted low-sodium chicken broth is also good.
If the constipation doesn't resolve on its own in a day or two, I would take your cat to your regular vet. He may need an enema to get rid of really hard stool. Then your vet can prescribe something like lactulose as a stool softener for long-term use, if needed.
Good luck!
Dr. Scarlett
I am a practicing small animal veterinarian with 14 years experience.
Anyway megat had a few licks of milk (before I went online of course) and now he is already in his night cage. I had always made his wet food dinner more soupy right after he had to have the sub qs. Maybe I would try the tuna ice cubes. :)
Pilling Megat
dear san
I feel that you should practise with offur cats more before trying to pill me with the yukky prednisone yourself. You were lucky this morning and on a second try at that..hee. You know I will try my very best not to eat that pill willingly and I know that you will always try to get me to take it. We will see which one offur us will be victorious! VIVA LA CHAT!
your chat
megat
Saturday, June 6, 2009
Prednisone blues
Thursday, June 4, 2009
Thursday Update
Megat taking in the breeze
Megat is feeling quite well. He is his sual self and very greedy, as always. I wonder how a cat that eats so much has become so thin. He is now 3.62 from 3.65. The office manager who helped Dr P to take his blood for the hematology tests was very surprised. "He is so thin! He used to be bigger!" she exclaimed.
He is usually very good at taking his meds but I guess the milk thistle does not taste good at all. This morning I thought I would try giving it to him myself but he spat it out. So I guess it would have to give it to him on alternate days. I could put it in his food but I do not want to mess with his prednisone.
Last night he was rather warm so i put the chilled water cushion for him. I was gld to see that his apetite was back and he ate his night snack and salmon treat happily.
Today he was his usual self, sitting with grandma and I and only tried to harass Toro once :) So maybe Dr P is right. The side effects of no appetite does not last long. This is good news as he cannot get any thinner I hope.
Wednesday, June 3, 2009
Letter to My Cat after his 1st chemo
Tuesday, June 2, 2009
1st Chemo for Megat
Dr P informed me of the chemo protocols and what was in his future if I elected for him to have chemo. He would have a cycle of 8 weeks of chemo before we would have to do an ultra sound to see if the chemo was having any positive effect on him. Megat would also have to have a blood test every week before the doc progress with anything else to see if it was possible for him to continue.
The side effects would be - vomitting, no appetite, listlessness and if he should lose any hair, it would be his whiskers only. But the doc said it was unlikely that he would lose any as it would be only in extreme cases. She said that cats go through chemo relatively well but she needed me to be sure that that was the way I wanted to go. Whatever I decide, she said that his hematology tests must allow me to make the decision as if it was not good, then no chemo would take place.
As usual Megat was very good at the blood letting and then we had to wait for the results.
Megat's hematology test was not so good.
WBC = 3.97 (5.5 to 19.5 normal); PLT is 33 (300-800 normal); but his RBC is ok at 6.26 (5 to 10 normal) However even if his WBC is 3.97, it was still more than 2.5, which makes it ok for his first round of chemo with Vincristine.
And so I had to make a decision for Megat. Dr P showed me his personal chemo protocol and what will be done when.
We are doing Vincristine which is an IV; prednisone (a steroid at home which he takes every day at 1.5 tablets a day); cyclophosphamide ( a tablet at home) and adramycine - an IV. We have to be at the hospital every tue and the doc would take his blood test to see if he could proceed for the whole first series.
02/06 - Vincristine (45 minute IV) + prednisolone (steroid pills)
09/06 - cyclophosphamide (IV) + prednisolone
16/06 - Vincristine (IV) + prednisone
23/06 - adriamycine (IV if possible - depends on his platelets) + prednisolone
30/06 - rest
07/07 - Vincristine
14/07 - cyclophosphamide
21/07 - Vincristine
28/07 - adriamcycine
End of 1st cycle - Ultra sound to check mass and organs
Milk Thistle
To be given to pet twice daily. One drop for every 2 lb (1 kg)
Please note that the product comes with an eye dropper to count out the drops. This dropper is marked at 0.5ML and 1ML. The 0.5ML line is equal to 10 drops.
Product can be given with food or directly in the mouth with eye dropper.
Product will last for 6 months. Please refrigerate after opening.